IT1133079B - Acidi 4 ammino & chinolincarbossilici e loro esteri particolarmente utili come antisecreitivi ed antiulcera - Google Patents

Acidi 4 ammino & chinolincarbossilici e loro esteri particolarmente utili come antisecreitivi ed antiulcera

Info

Publication number
IT1133079B
IT1133079B IT67465/80A IT6746580A IT1133079B IT 1133079 B IT1133079 B IT 1133079B IT 67465/80 A IT67465/80 A IT 67465/80A IT 6746580 A IT6746580 A IT 6746580A IT 1133079 B IT1133079 B IT 1133079B
Authority
IT
Italy
Prior art keywords
quinolincarbossils
secretive
ulcer
amino acids
particularly useful
Prior art date
Application number
IT67465/80A
Other languages
English (en)
Italian (it)
Other versions
IT8067465A0 (it
Inventor
Harry Randall Munson Jr
Stancil Alphin Reevis
Original Assignee
Robins Co Inc A H
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Robins Co Inc A H filed Critical Robins Co Inc A H
Publication of IT8067465A0 publication Critical patent/IT8067465A0/it
Application granted granted Critical
Publication of IT1133079B publication Critical patent/IT1133079B/it

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/48—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
    • C07D215/54—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 3
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Quinoline Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
IT67465/80A 1979-03-26 1980-03-26 Acidi 4 ammino & chinolincarbossilici e loro esteri particolarmente utili come antisecreitivi ed antiulcera IT1133079B (it)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US2398179A 1979-03-26 1979-03-26
US06/127,153 US4343804A (en) 1979-03-26 1980-03-04 4-Amino-3-quinolinecarboxylic acids and esters-antisecretory anti-ulcer compounds

Publications (2)

Publication Number Publication Date
IT8067465A0 IT8067465A0 (it) 1980-03-26
IT1133079B true IT1133079B (it) 1986-07-09

Family

ID=26697875

Family Applications (1)

Application Number Title Priority Date Filing Date
IT67465/80A IT1133079B (it) 1979-03-26 1980-03-26 Acidi 4 ammino & chinolincarbossilici e loro esteri particolarmente utili come antisecreitivi ed antiulcera

Country Status (31)

Country Link
US (1) US4343804A (en])
JP (1) JPH02117663A (en])
AR (1) AR230268A1 (en])
AT (1) AT372373B (en])
AU (1) AU528388B2 (en])
BR (1) BR8001779A (en])
CA (1) CA1147338A (en])
CH (1) CH644105A5 (en])
DE (1) DE3011490A1 (en])
DK (1) DK156056C (en])
EG (1) EG15009A (en])
ES (1) ES8103048A1 (en])
FI (1) FI77452C (en])
FR (1) FR2452485B1 (en])
GB (1) GB2047244B (en])
GR (1) GR68006B (en])
HK (1) HK67983A (en])
IE (1) IE49577B1 (en])
IL (1) IL59628A (en])
IN (1) IN151446B (en])
IT (1) IT1133079B (en])
MX (1) MX6264E (en])
NL (1) NL8001752A (en])
NO (1) NO153927C (en])
NZ (1) NZ193252A (en])
PH (1) PH16416A (en])
PL (1) PL125030B1 (en])
PT (1) PT71008B (en])
SE (1) SE435837B (en])
SG (1) SG33683G (en])
YU (1) YU41702B (en])

Families Citing this family (43)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8610981D0 (en) * 1986-05-06 1986-06-11 Ici America Inc Quinoline amides
GB8621425D0 (en) * 1986-09-05 1986-10-15 Smith Kline French Lab Compounds
GB8804448D0 (en) * 1988-02-25 1988-03-23 Smithkline Beckman Intercredit Compounds
GB8804445D0 (en) * 1988-02-25 1988-03-23 Smithkline Beckman Intercredit Compounds
GB8804444D0 (en) * 1988-02-25 1988-03-23 Smithkline Beckman Intercredit Compounds
GB8804447D0 (en) * 1988-02-25 1988-03-23 Smithkline Beckman Intercredit Compounds
GB8804446D0 (en) * 1988-02-25 1988-03-23 Smithkline Beckman Intercredit Compounds
GB8804443D0 (en) * 1988-02-25 1988-03-23 Smithkline Beckman Intercredit Compounds
US5432182A (en) * 1989-02-23 1995-07-11 Smithkline Beecham Intercredit B.V. Compounds substituted quinoline derivatives
CA2011086A1 (en) * 1989-03-17 1990-09-17 Karl-Heinz Geiss 2-alkyl-4-arylmethylaminoquinolines, the use thereof and drugs prepared therefrom
DE3917233A1 (de) * 1989-05-26 1990-11-29 Basf Ag 8-substituierte 4-(heterocyclylmethylamino)-chinoline, ihre verwendung und daraus hergestellte arzneimittel
GB8918265D0 (en) * 1989-08-10 1989-09-20 Smithkline Beckman Intercredit Compounds
US5362743A (en) * 1993-03-09 1994-11-08 Pfizer Inc. Aminoquinoline derivatives
IS4164A (is) * 1993-06-11 1994-12-12 Ab Astra Efnasambönd sem hindra flæði magasýru
US5556863A (en) * 1993-06-11 1996-09-17 Astra Aktiebolag Compound for gastric acid secretion inhibition
PL181782B1 (pl) * 1993-08-10 2001-09-28 Black James Foundation Nowe zwiazki i sposób wytwarzania nowych zwiazków PL
US5650415A (en) * 1995-06-07 1997-07-22 Sugen, Inc. Quinoline compounds
KR0169813B1 (ko) * 1995-07-12 1999-01-15 김종인 4-아미노-3-아실나프티리딘 유도체
US5760041A (en) * 1996-02-05 1998-06-02 American Cyanamid Company 4-aminoquinazoline EGFR Inhibitors
US6875769B2 (en) * 1996-05-23 2005-04-05 Pfizer Inc. Substituted6,6-hetero-bicyclicderivatives
US5929080A (en) * 1997-05-06 1999-07-27 American Cyanamid Company Method of treating polycystic kidney disease
US6251912B1 (en) 1997-08-01 2001-06-26 American Cyanamid Company Substituted quinazoline derivatives
US6323209B1 (en) 1997-11-06 2001-11-27 American Cyanamid Company Method of treating or inhibiting colonic polyps
CN1144786C (zh) 1998-09-29 2004-04-07 美国氰胺公司 作为蛋白质酪氨酸激酶抑制剂的取代的3-氰基喹啉
AU776933B2 (en) * 1999-12-28 2004-09-23 Eisai R&D Management Co., Ltd. Heterocyclic compounds having sulfonamide groups
US6521618B2 (en) 2000-03-28 2003-02-18 Wyeth 3-cyanoquinolines, 3-cyano-1,6-naphthyridines, and 3-cyano-1,7-naphthyridines as protein kinase inhibitors
US6576644B2 (en) * 2000-09-06 2003-06-10 Bristol-Myers Squibb Co. Quinoline inhibitors of cGMP phosphodiesterase
UA80393C2 (uk) 2000-12-07 2007-09-25 Алтана Фарма Аг Фармацевтична композиція, яка містить інгібітор фде 4, диспергований в матриці
MY140561A (en) * 2002-02-20 2009-12-31 Nycomed Gmbh Dosage form containing pde 4 inhibitor as active ingredient
PL377847A1 (pl) 2003-01-14 2006-02-20 Arena Pharmaceuticals Inc. 1,2,3-Tripodstawione pochodne arylowe i heteroarylowe jako modulatory metabolizmu oraz profilaktyka i leczenie związanych z nim zaburzeń takich jak cukrzyca i hiperglikemia
EP1606261B1 (en) 2003-03-10 2009-11-04 Nycomed GmbH Novel process for the preparation of roflumilast
MXPA06000554A (es) * 2003-07-14 2006-07-03 Arena Pharm Inc Derivados arilo y heteroarilo fusionados como moduladores del metabolismo y la profilaxis y tratamiento de trastornos relacionados con los mismos.
ES2421916T3 (es) * 2005-03-16 2013-09-06 Nycomed Gmbh Forma farmacéutica de sabor enmascarado que contiene roflumilast
WO2011022216A1 (en) * 2009-08-17 2011-02-24 High Point Pharmaceuticals, Llc Substituted pyridine derivatives, pharmaceutical compositions, and methods of use to treat oxidative stress
CN103221391B (zh) 2010-01-27 2018-07-06 艾尼纳制药公司 (R)-2-(7-(4-环戊基-3-(三氟甲基)苄基氧基)-1,2,3,4-四氢环戊二烯并[b]吲哚-3-基)乙酸及其盐的制备方法
PE20131371A1 (es) 2010-09-22 2013-11-25 Arena Pharm Inc Moduladores del receptor gpr119 y el tratamiento de trastornos relacionados con este
PT3242666T (pt) 2015-01-06 2024-12-09 Arena Pharm Inc Composto para utilização no tratamento de patologias relacionadas com o recetor s1p1
SI3310760T1 (sl) 2015-06-22 2023-02-28 Arena Pharmaceuticals, Inc. Kristalinična L-argininska sol (R)-2-(7-(4-ciklopentil-3-(trifluorometil)benziloksi)-1,2,3,4- tetrahidrociklo-penta(b)indol-3-il)ocetne kisline za uporabo pri motnjah, povezanih z receptorjem S1P1
CN109890793B (zh) * 2016-11-11 2022-11-18 拜耳动物保健有限责任公司 新的抗蠕虫药喹啉-3-甲酰胺衍生物
WO2018151873A1 (en) 2017-02-16 2018-08-23 Arena Pharmaceuticals, Inc. Compounds and methods for treatment of primary biliary cholangitis
EP3700527A4 (en) * 2017-10-25 2021-03-10 Children's Medical Center Corporation PAPD5 INHIBITORS AND METHOD OF USING THEM
JP7403472B2 (ja) 2018-05-09 2023-12-22 バイエル・アニマル・ヘルス・ゲゼルシャフト・ミット・ベシュレンクテル・ハフツング 新規キノリン誘導体
CA3102136A1 (en) 2018-06-06 2019-12-12 Arena Pharmaceuticals, Inc. Methods of treating conditions related to the s1p1 receptor

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3470186A (en) * 1967-06-02 1969-09-30 American Cyanamid Co Substituted 4-anilino-3-quinolinecarboxylic acids and esters
JPS4838712A (en]) * 1971-09-18 1973-06-07

Also Published As

Publication number Publication date
NO153927C (no) 1986-06-18
IT8067465A0 (it) 1980-03-26
AU528388B2 (en) 1983-04-28
IL59628A (en) 1983-06-15
US4343804A (en) 1982-08-10
DE3011490C2 (en]) 1988-12-22
CH644105A5 (fr) 1984-07-13
BR8001779A (pt) 1980-11-18
PT71008B (en) 1981-06-25
SG33683G (en) 1985-03-29
MX6264E (es) 1985-02-19
FR2452485B1 (fr) 1986-09-12
FR2452485A1 (fr) 1980-10-24
AT372373B (de) 1983-09-26
PL222993A1 (en]) 1981-01-30
FI800910A7 (fi) 1980-09-27
ATA156480A (de) 1983-02-15
SE435837B (sv) 1984-10-22
NL8001752A (nl) 1980-09-30
AR230268A1 (es) 1984-03-01
IN151446B (en]) 1983-04-23
NZ193252A (en) 1984-04-27
IL59628A0 (en) 1980-06-30
PH16416A (en) 1983-09-29
CA1147338A (en) 1983-05-31
PL125030B1 (en) 1983-03-31
AU5684880A (en) 1980-10-02
FI77452B (fi) 1988-11-30
NO800858L (no) 1980-09-29
YU41702B (en) 1987-12-31
NO153927B (no) 1986-03-10
IE800605L (en) 1980-09-26
GR68006B (en]) 1981-10-26
DK156056B (da) 1989-06-19
JPH02117663A (ja) 1990-05-02
YU84480A (en) 1983-10-31
HK67983A (en) 1983-12-23
FI77452C (fi) 1989-03-10
ES489887A0 (es) 1981-02-16
DK156056C (da) 1989-11-06
EG15009A (en) 1985-03-31
DK128380A (da) 1980-09-27
SE8002292L (sv) 1980-09-27
ES8103048A1 (es) 1981-02-16
GB2047244A (en) 1980-11-26
DE3011490A1 (de) 1981-03-12
IE49577B1 (en) 1985-10-30
GB2047244B (en) 1983-02-23
PT71008A (en) 1980-04-01

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